研究論文

腸の奥からの健康を考える研究所での取り組みの関連論文についての基本情報と参照先URLを掲載しております。

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  【A-1】From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

  Koh A, De Vadder F, Kovatcheva-Datchary P, Bäckhed F. From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites. Cell 2016; 165: 1332-1345.
• 大腸ラボ

  【A-2】Gut Microbial Metabolites Fuel Host Antibody Responses.

  Kim M, Qie Y, Park J, Kim CH. Gut Microbial Metabolites Fuel Host Antibody Responses. Cell Host Microbe 2016; 20: 202-14.
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  【A-3】Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification

  Sorbara M T, Dubin K, Littmann E R, Moody T U, Fontana E, Seok R et al. Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification J Exp Med 2019; 216: 84–98.
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  【A-4】Gut Microbiota and Cardiovascular Uremic Toxicities.

  Velasquez M T, Centron P, Barrows I, Dwivedi R, Raj D S. Gut Microbiota and Cardiovascular Uremic Toxicities. Toxins (Basel) 2018; 10: 287.
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  【A-5】The association of diet, gut microbiota and colorectal cancer: what we eat may imply what we get.

  Yang J, Yu J. The association of diet, gut microbiota and colorectal cancer: what we eat may imply what we get. Protein Cell 2018; 9: 474-487.
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  【A-6】Microbial ecology: human gut microbes associated with obesity.

  Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature 2006; 444: 1022-3.
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  【A-7】Richness of human gut microbiome correlates with metabolic markers.

  Le Chatelier E, Nielsen T, Qin J, Prifti E, Hildebrand F, Falony G, et al. Richness of human gut microbiome correlates with metabolic markers. Nature 2013; 500: 541-6.
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  【A-8】The composition of the gut microbiota shapes the colon mucus barrier.

  Jakobsson HE, Rodríguez-Piñeiro AM, Schütte A, Ermund A, Boysen P, Bemark M, et al. The composition of the gut microbiota shapes the colon mucus barrier. EMBO Rep 2015; 16: 164-77.
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  【A-9】MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells.

  Ohnmacht C, Park JH, Cording S, Wing JB, Atarashi K, Obata Y, et al. MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells. Science 2015; 349: 989-93.
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  【A-10】Gut dysbiosis and detection of "live gut bacteria" in blood of Japanese patients with type 2 diabetes.

  Sato J, Kanazawa A, Ikeda F, Yoshihara T, Goto H, Abe H, et al. Gut dysbiosis and detection of "live gut bacteria" in blood of Japanese patients with type 2 diabetes. Diabetes Care 2014; 37: 2343-50.
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  【A-11】Human gut microbes impact host serum metabolome and insulin sensitivity.

  Pedersen HK, Gudmundsdottir V, Nielsen HB, Hyotylainen T, Nielsen T, Jensen BA, et al. Human gut microbes impact host serum metabolome and insulin sensitivity. Nature 2016; 535: 376-81.
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  【A-12】Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.

  Tang WH, Wang Z, Levison BS, Koeth RA, Britt EB, Fu X, et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N Engl J Med 2013; 368: 1575-84.
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  【A-13】The microbiome, cancer, and cancer therapy.

  Helmink BA, Khan MAW, Hermann A, Gopalakrishnan V, Wargo JA. The microbiome, cancer, and cancer therapy. Nat Med 2019; 25: 377-388.
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  【A-14】The gut microbiome and liver cancer: mechanisms and clinical translation.

  Yu LX, Schwabe RF. The gut microbiome and liver cancer: mechanisms and clinical translation. Nat Rev Gastroenterol Hepatol 2017; 14: 527-539.
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  【A-15】Mental health: thinking from the gut.

  Schmidt C. Mental health: thinking from the gut. Nature 2015; 518: S12-5.
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  【A-16】Gut microbial metabolites in depression: understanding the biochemical mechanisms.

  Caspani G, Kennedy S, Foster JA, Swann J. Gut microbial metabolites in depression: understanding the biochemical mechanisms. Microb Cell 2019; 6: 454-481.
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  【A-17】Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders.

  Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, et al. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell 2013; 155: 1451-63.
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  【A-18】Gut microbiome composition is associated with temperament during early childhood.

  Christian LM, Galley JD, Hade EM, Schoppe-Sullivan S, Kamp Dush C, Bailey MT. Gut microbiome composition is associated with temperament during early childhood. Brain Behav Immun 2015; 45: 118-27.
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  【A-19】(Dis) Trust your gut: the gut microbiome in age-related inflammation, health, and disease.

  Buford T W. (Dis) Trust your gut: the gut microbiome in age-related inflammation, health, and disease. Microbiome 2017; 5: 80.
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  【A-20】食物繊維摂取量と死亡リスクの関連　―多目的コホート研究（JPHC研究）からの成果報告―

  国立研究開発法人 国立がん研究センター 社会と健康研究センター 予防研究グループ．食物繊維摂取量と死亡リスクの関連 ―多目的コホート研究（JPHC研究）からの成果報告―．2020 No.348
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  【A-21】Effects of probiotics, prebiotics, and synbiotics on human health.

  Markowiak P, Śliżewska K. Effects of probiotics, prebiotics, and synbiotics on human health. Nutrients 2017; 9: 1021.